4 minutes

PHQ-9, GAD-7, HADS, WHO-5… which self-questionnaires should be used to support the identification of mental health disorders?
One patient consults for persistent fatigue. Another mentions recurrent headaches. A third simply talks about a lack of energy, sleeping difficulties, or a loss of interest for several weeks.
These symptoms can have many causes. But they can also be accompanied by anxiety, a depressive episode, or psychological distress that is not necessarily expressed spontaneously during the consultation.
And the stakes are far from marginal.
In France, 15.6% of adults aged 18 to 79 experienced a major depressive episode in 2024, representing nearly one in six adults. Among those affected, 44% did not receive any care related to their mental health. The general practitioner remains the first professional consulted when care is sought. (1)
Anxiety is also common: 6.3% of adults aged 18 to 79 were affected by a generalized anxiety disorder in 2024, and nearly 30% of them did not seek any care for their mental health. (2)
The impact on the healthcare system is also considerable. In 2024, psychiatric illnesses and treatments accounted for 29.1 billion euros in expenses reimbursed by the Health Insurance, representing approximately 14% of all expenses analysed in its medicalised mapping. (3)
In this context, self-questionnaires can help structure the identification of certain symptoms and facilitate their exploration with the patient.
PHQ-9, GAD-7, HADS, WHO-5… which tool to use and in which situation?
Conclusion
Mental health self-questionnaires can be simple and useful tools to better identify certain symptoms before or during a consultation.
The PHQ-9 and PHQ-2 allow for the exploration of depressive symptoms. The GAD-7 and GAD-2 focus on anxiety. The HADS simultaneously explores anxiety and depressive symptoms and is of particular interest in patients who also have a somatic pathology. Finally, the WHO-5 takes a different approach by assessing psychological well-being.
However, they are not intended to replace the clinical interview.
Their value lies mainly in their ability to bring information to light, structure it, and facilitate dialogue with the patient.
Used prior to the consultation and interpreted by a healthcare professional, they can thus help to more easily integrate mental health into prevention and routine care.
(1) Santé publique France. Depressive episodes: prevalence and healthcare utilisation. Santé publique France Barometer: results of the 2024 edition.
(2) Santé publique France. Generalized anxiety disorder: prevalence and healthcare utilisation. Santé publique France Barometer: results of the 2024 edition.
(3) Caisse nationale de l’Assurance Maladie. Barthélémy P. et al. The drivers of health expenditure growth from 2015 to 2024: a medicalised analysis.
(4) Haute Autorité de Santé. Characterised depressive episode in adults: management in primary care – Diagnosis. October 2017.
(5) Kroenke K., Spitzer R.L., Williams J.B.W. The PHQ-9: Validity of a Brief Depression Severity Measure. Journal of General Internal Medicine, 2001;16(9):606-613.
(6) Department of Veterans Affairs / Department of Defense. VA/DoD Clinical Practice Guideline for Assessment and Management of Patients at Risk for Suicide. 2024.
(7) Kroenke K., Spitzer R.L., Williams J.B.W. The Patient Health Questionnaire-2: Validity of a Two-Item Depression Screener. Medical Care, 2003;41(11):1284-1292.
(8) Spitzer R.L., Kroenke K., Williams J.B.W., Löwe B. A Brief Measure for Assessing Generalized Anxiety Disorder: The GAD-7. Archives of Internal Medicine, 2006;166(10):1092-1097.
9) Aktürk Z. et al. Generalized Anxiety Disorder 7-item (GAD-7) and 2-item (GAD-2) scales for detecting anxiety disorders in adults. Cochrane Database of Systematic Reviews, 2025. Review of 48 studies and 19,228 participants.
(10) Zigmond A.S., Snaith R.P. The Hospital Anxiety and Depression Scale. Acta Psychiatrica Scandinavica, 1983;67(6):361-370.
(11) Bocéréan C., Dupret E. A validation study of the Hospital Anxiety and Depression Scale (HADS) in a large sample of French employees. BMC Psychiatry, 2014;14:354.
(12) Mapi Research Trust. Hospital Anxiety and Depression Scale (HADS) – instrument information and conditions of use.
(13) World Health Organization. The World Health Organization-Five Well-Being Index (WHO-5). 2024.
(14) University of New South Wales / Psychology Foundation of Australia. Depression Anxiety Stress Scales - DASS.
(15) Cohen S., Kamarck T., Mermelstein R. A Global Measure of Perceived Stress. Journal of Health and Social Behavior, 1983;24(4):385-396. Founding article of the Perceived Stress Scale (PSS).
(16) Kessler R.C. et al. K6 and K10 Scales. The K6 and K10 scales assess non-specific psychological distress and are available in self-administered and interviewer-administered versions. Harvard University.
(17) Beck A.T., Steer R.A., Brown G.K. Beck Depression Inventory-II (BDI-II). Pearson Assessments, 1996. A 21-item self-administered questionnaire designed to measure the severity of depressive symptoms; its use is subject to Pearson's commercial terms.
(18) Sheehan D.V. et al. The Mini-International Neuropsychiatric Interview (M.I.N.I.): The Development and Validation of a Structured Diagnostic Psychiatric Interview for DSM-IV and ICD-10. Journal of Clinical Psychiatry, 1998;59(Suppl 20):22-33. The MINI is a structured diagnostic interview and not a self-administered questionnaire.








